If priapism is not treated immediately, penile tissue damage and permanent loss of potency may result.
To avoid low blood pressure, do not take the 50-milligram or 100-milligram dose of Viagra within 4 hours of taking an alpha-blocking drug such as Cardura.
Another brand of sildenafil is Revatio, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.
The erectile response, as assessed by RigiScan®, generally increased with increasing sildenafil dose and plasma concentration.
This is consistent with ritonavir's marked effects on a broad range of P450 substrates.
Keep Viagra in its original container.
If priapism is not treated immediately, penile tissue damage and permanent loss of potency may result.
Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been rarely reported in people taking PDE5 inhibitors, including Viagra.
Mothers who are taking this medicine for pulmonary arterial hypertension and who wish to breast-feed should discuss this with their doctor.
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours.
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5 mmHg), (see CLINICAL PHARMACOLOGY: Pharmacodynamics).
In fixed-dose studies, dyspepsia (17%) and abnormal vision (11%) were more common at 100 mg than at lower doses.
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Even though this total dosage produced plasma sildenafil concentrations which were approximately 2 to 5 times higher than the mean maximum plasma concentrations following a single oral dose of 100 mg in healthy male volunteers, the hemodynamic response to exercise was preserved in these patients.
Analysis of the safety database showed no apparent difference in the side effect profile in patients taking Viagra with and without antihypertensive medication.
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Studies have produced relevant data on the effects of Viagra on cardiac output.
Read this information carefully before you start taking Viagra.
It is not known if the medicine is safe for use in these patients Conditions causing thickened blood or slower blood flow, including leukemia; multiple myeloma (tumors of the bone marrow); or polycythemia, sickle cell disease, and thrombocythemia (blood problems) or Priapism (history of)—Although sildenafil does not cause priapism (erection lasting longer than 6 hours), patients with these conditions have an increased risk of priapism and it could occur while using sildenafil Heart or blood disease—Sexual activity increases the heart rate and blood flow and can increase the chance of problems occurring for some patients who use any type of medicine, including sildenafil, that increases sexual ability Kidney problems (severe) or Liver problems (severe)—Chance of problems occurring may be increased.
In a separate drug interaction study, when amlodipine, 5 mg or 10 mg, and Viagra, 100 mg were orally administered concomitantly to hypertensive patients mean additional blood pressure reduction of 8 mmHg systolic and 7 mmHg diastolic were noted (see Drug Interactions).
These patients had erectile dysfunction at baseline that was characterized by median categorical scores of 2 (a few times) on principal IIEF questions.
Sildenafil was not carcinogenic when administered to mice for 18–21 months at dosages up to the Maximum Tolerated Dose (MTD) of 10 mg/kg/day, approximately 0.
If you experience sudden decrease or loss of vision, stop taking PDE5 inhibitors, including Viagra, and call a doctor right away.
For oral dosage form (tablets): o For treatment of erectile dysfunction: + Adults up to 65 years of age—50 mg as a single dose no more than once a day, 1 hour before sexual intercourse.
Others were reported to have occurred hours to days after the use of Viagra and sexual activity.
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It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors.
Sildenafil is also used to treat the symptoms of pulmonary arterial hypertension.
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Geriatric Use Healthy elderly volunteers (65 years or over) had a reduced clearance of sildenafil (see CLINICAL PHARMACOLOGY: Pharmacokinetics in Special Populations).
These effects may be worse if you take it with alcohol or certain medicines.
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Do not take Viagra if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, Minitran, Deponit, Transderm-Nitro), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket), or recreational drugs such as amyl nitrate or nitrite ("poppers").
It works by dilating blood vessels in the penis, allowing the inflow of blood needed for an erection.
Breast-feeding—It is not known whether sildenafil passes into breast milk.
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However, check with your doctor if any of the following side effects continue or are bothersome: More common Aches or pains in muscles; bloody nose; diarrhea; difficult or labored breathing; flushing; headache; nasal congestion; pain or tenderness around eyes and cheekbones; redness of skin; sneezing; stomach discomfort following meals; stuffy or runny nose; trouble in sleeping; unusually warm skin Rare Anxiety Note: The following rare side effects have not been completely established as being caused by sildenafil Abdominal pain; abnormal dreams; clumsiness or unsteadiness; cough; diarrhea or stomach cramps (severe or continuing); difficulty in swallowing; ear pain; increased amount of saliva; increased skin sensitivity; lack of coordination; loss of bladder control; mental depression; nausea; numbness or tingling of hands, legs, or feet; rectal bleeding; redness or irritation of the tongue; redness, soreness, swelling, or bleeding of gums; ringing or buzzing in ears; sensation of motion, usually whirling, ei
Do not take Viagra if you are also using a nitrate drug for chest pain or heart problems.
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Do not keep outdated medicine or medicine no longer needed.
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It can help many men who have erectile dysfunction get and keep an erection when they become sexually excited (stimulated).
If you have heart problems severe enough to make sexual activity a danger, you should avoid using Viagra.
Therefore, the use of such combinations is not recommended.
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If you take Viagra with any nitrate medicine or recreational drug containing nitrates, your blood pressure could suddenly drop to an unsafe level.
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Viagra may cause other side effects besides those listed on this sheet.
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For oral dosage form (tablets): o For treatment of erectile dysfunction: + Adults up to 65 years of age—50 mg as a single dose no more than once a day, 1 hour before sexual intercourse.
How should you take Viagra?
Sildenafil is not indicated for use in women for erectile dysfunction.
However, Viagra is not for everyone.