Symptoms of a heart attack may include chest, shoulder, neck, or jaw pain; numbness of an arm or leg; severe dizziness, headache, nausea, stomach pain, or vomiting; fainting; or vision changes.
Twenty subjects received Viagra 50 mg, but only 19 subjects received matching placebo.
There were three subjects with a decrease from baseline in standing systolic BP >30mmHg following Viagra 25 mg, one subject with a decrease from baseline in standing systolic BP > 30 mmHg following placebo and two subjects with a decrease from baseline in standing systolic BP > 30 mmHg following both Viagra and placebo.
Larger effects were recorded among patients receiving concomitant nitrates (see CONTRAINDICATIONS).
Therefore, when Viagra is co-administered with alpha-blockers, patients should be stable on alpha-blocker therapy prior to initiating Viagra treatment and Viagra should be initiated at the lowest dose.
Patients with heart problems who take Viagra may be at increased risk for heart-related side effects, including heart attack or stroke.
All three were taking Viagra 100 mg, and all three reported mild adverse events at the time of reductions in standing SBP, including vasodilation and lightheadedness.
Before taking Viagra, tell your doctor about all other medications you use for erectile dysfunction, or if you are using any of the following medications: an antibiotic such as clarithromycin (Biaxin), clotrimazole (Mycelex Troche), dalfopristin/quinupristin (Synercid), erythromycin (E.
If your partner may become pregnant and you wish to avoid pregnancy, be sure to use an effective form of birth control.
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Storage—To store this medicine: Keep out of the reach of children.
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Contact your doctor or seek medical attention right away if you experience these symptoms.
If you are or will be breast-feeding while you use Viagra , check with your doctor.
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Viagra is only for patients with erectile dysfunction.
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Precautions While Using This Medicine Sildenafil has not been studied with other medicines used for treatment of erectile dysfunction.
Geriatric Use Healthy elderly volunteers (65 years or over) had a reduced clearance of sildenafil (see CLINICAL PHARMACOLOGY: Pharmacokinetics in Special Populations).
Sit or lie down at the first sign of any of these effects.
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These results demonstrated that the effect of Viagra on the primary endpoint was statistically non-inferior to placebo.
Viagra is not recommended for use in CHILDREN; safety and effectiveness in children have not been confirmed.
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Discuss any possible risks to your baby.
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In fixed-dose studies, dyspepsia (17%) and abnormal vision (11%) were more common at 100 mg than at lower doses.
Hemic and Lymphatic: anemia and leukopenia.
Effects of Viagra on Cardiac Parameters Single oral doses of sildenafil up to 100 mg produced no clinically relevant changes in the ECGs of normal male volunteers.
In these two subjects, hypotension was reported as a moderately severe adverse event, beginning at approximately 1 hour after administration of Viagra 50 mg and resolving after approximately 7.
The frequency of patients reporting improvement of erections in response to a global question in four of the randomized, double-blind, parallel, placebo-controlled fixed dose studies (1797 patients) of 12 to 24 weeks duration is shown in Figure 4.
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In these studies, involving about 1600 patients, analyses of patient diaries showed no effect of Viagra on rates of attempted intercourse (about 2 per week), but there was clear treatment-related improvement in sexual function: per patient weekly success rates averaged 1.
An erection will not occur just by taking a pill.
Taking Viagra with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack.
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Overdosage In studies with healthy volunteers of single doses up to 800 mg, adverse events were similar to those seen at lower doses but incidence rates and severities were increased.
Contact your doctor right away if you have an erection that lasts more than 4 hours.
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Doses range from 25 milligrams to 100 milligrams, depending on the drug's effect.
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If any develop or change in intensity, inform your doctor as soon as possible.
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Respiratory: asthma, dyspnea, laryngitis, pharyngitis, sinusitis, bronchitis, sputum increased, cough increased.
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This sheet is only a summary.
Urogenital: prolonged erection, priapism (see WARNINGS), and hematuria.
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Mean resting values for right atrial pressure, pulmonary artery pressure, pulmonary artery occluded pressure and cardiac output decreased by 28%, 28%, 20% and 7% respectively.
However, Viagra may be taken anywhere from 4 hours to 0.
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Single doses of antacid (magnesium hydroxide/aluminum hydroxide) did not affect the bioavailability of Viagra.
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Urogenital: prolonged erection, priapism (see WARNINGS), and hematuria.
Non-arteritic anterior ischemic optic neuropathy (NAION), a cause of decreased vision including permanent loss of vision, has been reported rarely post-marketing in temporal association with the use of phosphodiesterase type 5 (PDE5) inhibitors, including Viagra.
Treating erectile dysfunction (ED).
Patients on multiple antihypertensive medications were included in the pivotal clinical trials for Viagra.
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Heat or moisture may cause the medicine to break down.