If you want more information or develop any side effects or symptoms you are concerned about, call your doctor.
Without physical action to the penis, such as that occurring during sexual intercourse, sildenafil will not work to cause an erection.
Before taking Viagra, tell your doctor if you are allergic to any drugs, or if you have If you have any of these conditions, you may need a dose adjustment or special tests to safely take Viagra.
If needed, your doctor may increase your daily dose to 100 mg or decrease your daily dose to 25 mg.
Based on the pharmacokinetic profile of a single 100 mg oral dose given to healthy normal volunteers, the plasma levels of sildenafil at 24 hours post dose are approximately 2 ng/mL (compared to peak plasma levels of approximately 440 ng/mL) (see CLINICAL PHARMACOLOGY: Pharmacokinetics and Metabolism).
Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence).
You will need to have a thorough medical exam to diagnose your erectile dysfunction and to find out if you can safely take Viagra alone or with your other medicines.
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Use barrier methods of birth control (eg, condoms) if you have HIV infection or an STD.
There is no controlled clinical data on the safety or efficacy of Viagra in the following groups; if prescribed, this should be done with caution.
Pregnancy Category B No evidence of teratogenicity, embryotoxicity or fetotoxicity was observed in rats and rabbits which received up to 200 mg/kg/day during organogenesis.
The penis cannot fill with enough blood.
Ask your health care provider any questions you may have about how to use Viagra .
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It is not known if the medicine is safe for use in these patients Conditions causing thickened blood or slower blood flow, including leukemia; multiple myeloma (tumors of the bone marrow); or polycythemia, sickle cell disease, and thrombocythemia (blood problems) or Priapism (history of)—Although sildenafil does not cause priapism (erection lasting longer than 6 hours), patients with these conditions have an increased risk of priapism and it could occur while using sildenafil Heart or blood disease—Sexual activity increases the heart rate and blood flow and can increase the chance of problems occurring for some patients who use any type of medicine, including sildenafil, that increases sexual ability Kidney problems (severe) or Liver problems (severe)—Chance of problems occurring may be increased.
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There were no reports of syncope among these patients.
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This could happen even when you are not having sex.
Read the directions carefully before using the medicine .
If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
If you are or will be breast-feeding while you use Viagra , check with your doctor.
If you are taking a protease inhibitor, your dose may be adjusted (please see Finding the Right Dose for You).
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The penis then expands and hardens.
For the 20 subjects who received Viagra 100 mg and matching placebo, the placebo-subtracted mean maximum decreases from baseline (95% CI) in systolic blood pressure were as follows: Blood pressure was measured after administration of Viagra at the same times as those specified for the previous doxazosin studies.
Geriatric Use Healthy elderly volunteers (65 years or over) had a reduced clearance of sildenafil (see CLINICAL PHARMACOLOGY: Pharmacokinetics in Special Populations).
Alternatively, the medicine may be taken 30 minutes to 4 hours before sexual intercourse.
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Digestive: vomiting, glossitis, colitis, dysphagia, gastritis, gastroenteritis, esophagitis, stomatitis, dry mouth, liver function tests abnormal, rectal hemorrhage, gingivitis.
7 seconds for sildenafil (N=70) and placebo, respectively.
Its effect is more potent on PDE5 than on other known phosphodiesterases (10-fold for PDE6, >80-fold for PDE1, >700-fold for PDE2, PDE3, PDE4, PDE7, PDE8, PDE9, PDE10, and PDE11).
However, Viagra is not for everyone.
Viagra may not work as quickly if you take it with a high-fat meal.
In the titration studies (n=644) (with most patients eventually receiving 100 mg), results were similar.
If your symptoms do not improve or if they become worse, check with your doctor.
This includes nitroglycerin.
Viagra relaxes muscles and increases blood flow to particular areas of the body.
Be sure that any discarded medicine is out of the reach of children.
The primary measure in the principal studies was a sexual function questionnaire (the International Index of Erectile Function - IIEF) administered during a 4-week treatment-free run-in period, at baseline, at follow-up visits, and at the end of double-blind, placebo-controlled, at-home treatment.
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Viagra is an oral drug for male impotence, also known as erectile dysfunction (ED).
Take Viagra exactly as it was prescribed for you.
If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
This includes prescription and nonprescription medicines or remedies: Remember, Viagra should never be used with medicines that contain nitrates (see Viagra Is Not for Everyone).
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You could be having a serious side effect of Viagra.
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The frequency of patients reporting improvement of erections in response to a global question in four of the randomized, double-blind, parallel, placebo-controlled fixed dose studies (1797 patients) of 12 to 24 weeks duration is shown in Figure 4.
Clinical Studies In clinical studies, Viagra was assessed for its effect on the ability of men with erectile dysfunction (ED) to engage in sexual activity and in many cases specifically on the ability to achieve and maintain an erection sufficient for satisfactory sexual activity.
You could be having a serious side effect of Viagra.
In some of the cases, medical conditions and other factors were reported that may have also played a role in the otologic adverse events.
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Diary data indicated that on Viagra, 48% of intercourse attempts were successful versus 12% on placebo.
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Permanent damage and impotence could result.
An extra patient leaflet is available with Viagra .
In addition, in a study performed in healthy male volunteers, coadministration of the HIV protease inhibitor saquinavir, also a CYP3A4 inhibitor, at steady state (1200 mg tid) with Viagra (100 mg single dose) resulted in a 140% increase in sildenafil Cmax and a 210% increase in sildenafil AUC.
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Do not take Viagra if you are also using a nitrate drug for chest pain or heart problems.
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Taking Viagra with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack.